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Article

CTLA4 gene polymorphisms are associated with chronic bronchitis.

The European respiratory journal - 1 Sept 2009

Zhu G, Agusti A, Gulsvik A, Bakke P, Coxson H, Lomas D A, Silverman E K, Pillai S G

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is characterised by chronic and progressive dyspnoea, cough and sputum production. T-lymphocytes may play a key role in the pathogenesis of COPD and chronic bronchitis. Cytotoxic T-lymphocyte antigen (CTLA) 4 is a potential candidate gene because it modulates T-cell activation. Genetic association between nine CTLA4 single nucleotide polymorphisms (SNPs) and chronic...

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Source

Identifiers

PMID: 19386687
DOI: 10.1183/09031936.00141808

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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