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Article

The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).

Human molecular genetics - 1 Aug 2004

Celedón Juan C, Lange Christoph, Raby Benjamin A, Litonjua Augusto A, Palmer Lyle J, DeMeo Dawn L, Reilly John J, Kwiatkowski David J, Chapman Harold A, Laird Nan, Sylvia Jody S, Hernandez Melvin, Speizer Frank E, Weiss Scott T, Silverman Edwin K

Abstract excerpt

Although cigarette smoking is the primary environmental risk factor, genetic risk factors likely influence the development of chronic obstructive pulmonary disease (COPD). Linkage analysis between short-tandem repeat markers on chromosome 19 and COPD phenotypes was followed by association analysis of single nucleotide polymorphisms in a gene on chromosome 19q [transforming growth factor-beta1 (TGFB1)] and COPD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15175276
DOI: 10.1093/hmg/ddh171

Genes

TGFB1
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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