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Article

Association of plasma soluble CTLA-4 with lung function and gene polymorphism in Chinese asthmatic children.

International archives of allergy and immunology - 1 Jan 2010

Chan Iris H S, Tang Nelson L S, Leung Ting F, Lam Yvonne Y O, Wong Gary W K, Wong Chun K, Lam Christopher W K

Abstract excerpt

BACKGROUND: Cytotoxic T lymphocyte antigen 4 (CTLA-4) is known to downregulate the T(H)2 immune response. Recent studies have suggested an association of CTLA-4 polymorphisms with allergic diseases. We investigated the effects of single nucleotide polymorphisms (SNPs) of CTLA-4 on asthma traits and plasma sCTLA-4 in 298 Chinese asthmatic children and 175 controls. METHODS: Plasma sCTLA-4, total and...

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Source

Identifiers

PMID: 20016193
DOI: 10.1159/000265532

Genes

FEV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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