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Article

Genetic variation in interleukin-17 receptor A is functionally associated with chronic rejection after lung transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Dec 2013

Ruttens David, Wauters Els, Kiciński Michal, Verleden Stijn E, Vandermeulen Elly, Vos Robin, Van Raemdonck Dirk E, Nawrot Tim S, Lambrechts Diether, Verleden Geert M, Vanaudenaerde Bart M

Abstract excerpt

BACKGROUND: Chronic rejection is the major cause of morbidity and mortality after lung transplantation. Interleukin (IL)-17-producing cells, inducers of airway neutrophilia, play a prominent role in chronic rejection. METHODS: We investigated the association between genetic variants in the IL-17/IL-23 pathway and outcome after lung transplantation. Six genetic variants in IL-17 and IL-23 receptor genes were...

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Identifiers

PMID: 24263024
DOI: 10.1016/j.healun.2013.09.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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