Article
TNFA-863 polymorphism is associated with a reduced risk of chronic obstructive pulmonary disease: a replication study.
BMC medical genetics - 10 Oct 2011
Córdoba-Lanús Elizabeth, Baz-Dávila Rebeca, de-Torres Juan P, Rodríguez-Pérez María C, Maca-Meyer Nicole, Varo Nerea, Medina-Coello Chaxiraxi, Aguirre-Jaime Armando, Casanova Ciro
Abstract excerpt
UNLABELLED: : BACKGROUND: TNF-α mediated inflammation is thought to play a key role in the respiratory and systemic features of Chronic Obstructive Pulmonary Disease. The aim of the present study was to replicate and extend recent findings in Taiwanese and Caucasian populations of associations between COPD susceptibility and variants of the TNFA gene in a Spanish cohort. METHODS: The 3 reported SNPs were...
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