Article
CTLA-4 gene polymorphisms and susceptibility to chronic obstructive pulmonary disease.
International journal of clinical and experimental pathology - 1 Jan 2013
Deng Lijing, Zhou Haixia, Yang Jing, Xiao Jun, Wang Bo, Wang Lan, Ou Xuemei, Feng Yulin
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate whether four single nucleotide polymorphisms (SNPs) in CTLA-4 gene are associated with chronic obstructive pulmonary disease (COPD) in a Chinese population. METHODS: Samples were collected from a Chinese population and analyzed for the association of SNPs in CTLA-4 gene with COPD in a case-control study. Four SNPs (rs231775, rs3087243, rs231725, rs5742909) in...
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