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Article

CTLA4 and CD86 gene polymorphisms and susceptibility to chronic obstructive pulmonary disease.

Human immunology - 1 Nov 2010

Liu Yun, Liang Wei-Bo, Gao Lin-Bo, Pan Xin-Min, Chen Tian-Yi, Wang Yan-Yun, Xue Hui, Zhang Lu-shun, Zhang Lin

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) may be related to chronic inflammation and immune-mediated conditions, and its pathogenesis involves T-cell activation and proliferation. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and costimulatory molecules (CD80/CD86) genes are important mediators of T-cell activation in the immune response. The aim of this study was to investigate whether +2379G/C...

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Source

Identifiers

PMID: 20732370
DOI: 10.1016/j.humimm.2010.08.007

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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