Article
Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease.
Respiratory research - 21 Sept 2014
Lee Jin Hwa, Cho Michael H, Hersh Craig P, McDonald Merry-Lynn N, Crapo James D, Bakke Per S, Gulsvik Amund, Comellas Alejandro P, Wendt Christine H, Lomas David A, Kim Victor, Silverman Edwin K
Abstract excerpt
BACKGROUND: Chronic bronchitis (CB) is one of the classic phenotypes of COPD. The aims of our study were to investigate genetic variants associated with COPD subjects with CB relative to smokers with normal spirometry, and to assess for genetic differences between subjects with CB and without CB within the COPD population. METHODS: We analyzed data from current and former smokers from three cohorts: the COPDGene...
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