Article
Potential contributions of antimutator activity to the metastasis suppressor function of NM23-H1.
Molecular and cellular biochemistry - 1 Sept 2009
Kaetzel David M, McCorkle Joseph R, Novak Marian, Yang Mengmeng, Jarrett Stuart G
Abstract excerpt
nm23-h1 is a well-documented metastasis suppressor gene whose mechanism(s) of action have yet to be fully elucidated. The purpose of this report is to discuss recent advances in investigating the potential role of a novel 3'-5' exonuclease activity identified recently in our laboratory, a biochemical function associated, in general, with DNA repair and replication. We have employed a site-directed mutagenesis...
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