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Article

Mutations at the dimer interface and surface residues of Nm23-H1 metastasis suppressor affect its expression and function.

Molecular and cellular biochemistry - 1 Nov 2020

Li Yuanjun, Liu Wen, Saini Vasu, Wong Yung H

Abstract excerpt

The Nm23 metastasis suppressor family is involved in a variety of physiological and pathological processes including cell proliferation, differentiation, tumorigenesis, and metastasis. Given that Nm23 proteins may function as hexamers composed of different members of the family, especially Nm23-H1 and H2 isoforms, it is pertinent to assess the importance of interface and surface residues in defining the...

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PMID: 32705629
DOI: 10.1007/s11010-020-03836-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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