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Article

Genomic PCR-SSCP analysis of the metastasis associated NM23-H1 (NME1) gene: a study on colorectal cancer.

Anticancer research - 1 Jan 2000

Bafico A, Varesco L, De Benedetti L, Caligo M A, Gismondi V, Sciallero S, Aste H, Ferrara G B, Bevilacqua G

Abstract excerpt

To facilitate further mutational analysis of NM13-H1, a human metastasis suppressor gene, we have established its genomic organization. NM23-H1 is composed of five exons, spanning a genomic DNA fragment of 10 kb. Using oligonucleotide primers flanking each exon, PCR-SSCP analysis was performed on genomic DNAs of healthy individuals. A common polymorphism, a C to T transition, was detected 30 nucleotides upstream...

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PMID: 8297127

Genes

NME1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genomic PCR-SSCP analysis of the metastasis associated NM23-H1 (NME1) gene: a study on colorectal cancer.PMID 8297127Read ↗

Mutation in the nm23 gene is associated with metastasis in colorectal cancer.Semantic proximity Read ↗

Somatic allelic deletion of nm23 in human cancer.Semantic proximity Read ↗

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[Correlation study of allelic gene deletion of nm23-H1 and human colorectal carcinoma metastasis].Semantic proximity Read ↗

Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas.Semantic proximity Read ↗

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The metastasis suppressor NM23-H1 possesses 3'-5' exonuclease activity.Semantic proximity Read ↗

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