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Article

Potential roles of 3'-5' exonuclease activity of NM23-H1 in DNA repair and malignant progression.

Journal of bioenergetics and biomembranes - 1 Aug 2006

Kaetzel David M, Zhang Qingbei, Yang Mengmeng, McCorkle Joseph R, Ma Deqin, Craven Rolf J

Abstract excerpt

NM23-H1 is a metastasis suppressor protein that exhibits 3'-5' exonuclease activity in vitro. As 3'-5' exonucleases are generally required for maintenance of genome integrity, this activity represents a plausible candidate mediator of the metastasis suppressor properties of the NM23-H1 molecule. Consistent with an antimutator function, ablation of the yeast NM23 homolog, YNK1, results in increased mutation rates...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17039395
DOI: 10.1007/s10863-006-9040-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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