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Article

Mutation in the nm23 gene is associated with metastasis in colorectal cancer.

Cancer research - 15 Feb 1993

Wang L, Patel U, Ghosh L, Chen H C, Banerjee S

Abstract excerpt

The human nm23 gene, a candidate metastatic suppressor gene, consists of two genes, nm23-H1 and nm23-H2. The potential mutation in the nm23-H1 gene was examined in colorectal cancer using a reverse transcription polymerase chain reaction amplification followed by DNA sequencing analysis. Genomic alterations in the nm23 gene were also examined by Southern hybridization. Genetic alterations either as a deletion in...

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PMID: 7916650

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Mutation in the nm23 gene is associated with metastasis in colorectal cancer.PMID 7916650Read ↗

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