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Article

NAD and axon degeneration: From the Wlds gene to neurochemistry

1 Jan 2009

Abstract excerpt

Neurodegenerative diseases have become a global issue due to the aging population. These disorders affect a vast patient population and represent a huge area of unmet therapeutic need. Axon degeneration is a common pathological character of those neurodegenerative diseases. It results in the loss of communication between neurons. Two decades ago, the Wallerian degeneration slow (Wlds) mouse strain was identified,...

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PMID: 19372760
DOI: 10.4161/cam.3.1.7483

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NAD and axon degeneration: From the Wlds gene to neurochemistryPMID 19372760Read ↗

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