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Article

Genetic variation in cell cycle and apoptosis related genes and multiple myeloma risk.

Leukemia research - 1 Dec 2009

Hosgood H Dean, Baris Dalsu, Zhang Yawei, Berndt Sonja I, Menashe Idan, Morton Lindsay M, Lee Kyoung-Mu, Yeager Meredith, Zahm Shelia H, Chanock Stephen, Zheng Tongzhang, Lan Qing

Abstract excerpt

Genetic variation may be an important risk factor for multiple myeloma. A hallmark of tumor formation and growth is cell cycle dysregulation and apoptosis avoidance. We previously reported the association of genetic variation in caspase genes, the apoptotic-regulating family, and multiple myeloma risk. To further examine if genetic variation in key cell cycle and apoptosis genes alters multiple myeloma risk, we...

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Source

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Identifiers

PMID: 19362737
DOI: 10.1016/j.leukres.2009.03.013
PMCID: PMC2749910

Genes

BAX
CASP9
RIPK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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