Article
Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut.
American journal of hematology - 1 Aug 2010
Lee Kyoung-Mu, Baris Dalsu, Zhang Yawei, Hosgood H Dean, Menashe Idan, Yeager Meredith, Zahm Shelia Hoar, Wang Sophia S, Purdue Mark P, Chanock Stephen, Zheng Tongzhang, Rothman Nathaniel, Lan Qing
Abstract excerpt
In light of the relationship between immune system dysregulation and multiple myeloma (MM) risk, we investigated whether genetic variation in 92 immune function genes among 77 gene regions are associated with MM susceptibility in a population-based case-control study (108 cases and 482 controls) conducted among Caucasian women in Connecticut. Tagging single-nucleotide polymorphisms (SNPs; N = 870) were selected...
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