Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.

doi:10.1158/1055-9965.EPI-13-1115

Article

Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2014

Martino Alessandro, Campa Daniele, Jurczyszyn Artur, Martínez-López Joaquín, Moreno María José, Varkonyi Judit, Dumontet Charles, García-Sanz Ramón, Gemignani Federica, Jamroziak Krzysztof, Stępieł Anna, Jacobsen Svend E Hove, Andersen Vibeke, Jurado Manuel, Landi Stefano, Rossi Anna Maria, Lesueur Fabienne, Marques Herlander, Dudziński Marek, Wątek Marzena, Moreno Victor, Orciuolo Enrico, Petrini Mario, Reis Rui Manuel, Ríos Rafael, Sainz Juan, Vogel Ulla, Buda Gabriele, Vangsted Annette Juul, Canzian Federico

Abstract excerpt

BACKGROUND: Genetic background plays a role in multiple myeloma susceptibility. Several single-nucleotide polymorphisms (SNP) associated with genetic susceptibility to multiple myeloma were identified in the last years, but only a few of them were validated in independent studies. METHODS: With the aim to conclusively validate the strongest associations so far reported, we selected the polymorphisms rs2227667...

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Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.

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