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Article

Genetic determinants of multiple myeloma risk within the Wnt/beta-catenin signaling pathway.

Cancer epidemiology - 1 Aug 2021

Belachew Alem A, Wu Xifeng, Callender Rashida, Waller Rosalie, Orlowski Robert Z, Vachon Celine M, Camp Nicola J, Ziv Elad, Hildebrandt Michelle A T

Abstract excerpt

BACKGROUND: Aberrant Wnt/beta-catenin pathway activation is implicated in Multiple Myeloma (MM) development, but little is known if genetic variants within this pathway contribute to MM susceptibility. METHODS: We performed a discovery candidate pathway analysis in 269 non-Hispanic white MM cases and 272 controls focusing on 171 variants selected from 26 core genes within the Wnt/beta-catenin pathway. Significant...

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Identifiers

PMID: 34216957
DOI: 10.1016/j.canep.2021.101972
PMCID: PMC8351401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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