Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in innate immunity genes and risk of multiple myeloma.

Hematological oncology - 1 Mar 2011

Purdue Mark P, Lan Qing, Menashe Idan, Zheng Tongzhang, Zhang Yawei, Yeager Meredith, Hosgood H Dean, Zahm Shelia H, Chanock Stephen J, Rothman Nathaniel, Baris Dalsu

Abstract excerpt

Multiple myeloma (MM) is a B-cell lymphoid malignancy suspected to be associated with immunologic factors. Given recent findings associating single-nucleotide polymorphisms (SNPs) in innate immunity genes with non-Hodgkin lymphoma, we conducted an investigation of innate immune gene variants using specimens from a population-based case-control study of MM conducted in Connecticut women. Tag SNPs (N = 1461)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatocyte Growth Factor

Share to Immunity, Innate

Share to Multiple Myeloma

Share to Plasminogen Activator Inhibitor 1

Share to Receptors, CCR7

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 20658475
DOI: 10.1002/hon.954
PMCID: PMC2980579

Genes

HGF
SERPINE1
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in innate immunity genes and risk of multiple myeloma.PMID 20658475Read ↗

Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut.Semantic proximity Read ↗

Common variants in genes that mediate immunity and risk of multiple myeloma.Semantic proximity Read ↗

Deciphering the genetics and mechanisms of predisposition to multiple myeloma.Semantic proximity Read ↗

Germline and somatic genetic effects on gene expression and outcome in patients with Multiple MyelomaSemantic proximity Read ↗

Fine Mapping of MHC Region Identifies Novel Susceptibility Loci in Multiple Myeloma When Comparing With Its Precursor Monoclonal Gammopathy of Unknown Significance.Semantic proximity Read ↗

Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression.Semantic proximity Read ↗

Identification of novel genetic loci for risk of multiple myeloma by functional annotationSemantic proximity Read ↗

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.Semantic proximity Read ↗

Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.Semantic proximity Read ↗

Sequencing at lymphoid neoplasm susceptibility loci maps six myeloma risk genes.Semantic proximity Read ↗

Racial/ethnic disparities in inflammatory gene single-nucleotide polymorphisms as predictors of a high risk for symptom burden in patients with multiple myeloma 1 year after diagnosis.Semantic proximity Read ↗

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.