Article
Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival.
BMC medicine - 8 Sept 2008
Van Ness Brian, Ramos Christine, Haznadar Majda, Hoering Antje, Haessler Jeff, Crowley John, Jacobus Susanna, Oken Martin, Rajkumar Vincent, Greipp Philip, Barlogie Bart, Durie Brian, Katz Michael, Atluri Gowtham, Fang Gang, Gupta Rohit, Steinbach Michael, Kumar Vipin, Mushlin Richard, Johnson David, Morgan Gareth
Abstract excerpt
BACKGROUND: We have engaged in an international program designated the Bank On A Cure, which has established DNA banks from multiple cooperative and institutional clinical trials, and a platform for examining the association of genetic variations with disease risk and outcomes in multiple myeloma. We describe the development and content of a novel custom SNP panel that contains 3404 SNPs in 983 genes,...
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