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Article

Development of a non invasive NGF-based therapy for Alzheimer's disease.

Current Alzheimer research - 1 Apr 2009

Covaceuszach Sonia, Capsoni Simona, Ugolini Gatsuella, Spirito F, Vignone D, Cattaneo Antonio

Abstract excerpt

Nerve growth factor (NGF) deficits are linked to Alzheimer's Disease (AD), due to the role of NGF on basal forebrain cholinergic neurons (BFCN). We have further established that a disequilibrium in NGF signaling and/or processing from its precursor proNGF is also directly and causally related to the aberrant activation of an amyloidogenic route to neurodegeneration. The therapeutic potential of using human NGF to...

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Source

Identifiers

PMID: 19355851
DOI: 10.2174/156720509787602870

Genes

NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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