Article
Potential role of phenotypic mutations in the evolution of protein expression and stability.
Proceedings of the National Academy of Sciences of the United States of America - 14 Apr 2009
Goldsmith Moshe, Tawfik Dan S
Abstract excerpt
Phenotypic mutations (errors occurring during protein synthesis) are orders of magnitude more frequent than genetic mutations. Consequently, the sequences of individual protein molecules transcribed and translated from the same gene can differ. To test the effects of such mutations, we establishe...
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