Article
Universally high transcript error rates in bacteria.
eLife - 29 May 2020
Li Weiyi, Lynch Michael
Abstract excerpt
Errors can occur at any level during the replication and transcription of genetic information. Genetic mutations derived mainly from replication errors have been extensively studied. However, fundamental details of transcript errors, such as their rate, molecular spectrum, and functional effects, remain largely unknown. To globally identify transcript errors, we applied an adapted rolling-circle sequencing...
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