Article
Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex.
Genes and immunity - 1 Jun 2009
Viken M K, Blomhoff A, Olsson M, Akselsen H E, Pociot F, Nerup J, Kockum I, Cambon-Thomsen A, Thorsby E, Undlien D E, Lie B A
Abstract excerpt
The high-risk human leukocyte antigen (HLA)-DRB1, DQA1 and DQB1 alleles cannot explain the entire type 1 diabetes (T1D) association observed within the extended major histocompatibility complex. We have earlier identified an association with D6S2223, located 2.3 Mb telomeric of HLA-A, on the DRB1(*)03-DQA1(*)0501-DQB1(*)0201 haplotype, and this study aimed to fine-map the associated region also on the...
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