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Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLA-DQB1, -DQA1 and -DRB1.

Genes and immunity - 1 Jan 2003

Johansson S, Lie B A, Todd J A, Pociot F, Nerup J, Cambon-Thomsen A, Kockum I, Akselsen H E, Thorsby E, Undlien D E

Abstract excerpt

Susceptibility to, and protection against development of type 1 diabetes (T1D) are primarily associated with the highly polymorphic exon 2 sequences of the HLA class II genes: DQB1, DQA1 and DRB1. However, several studies have also suggested that additional genes in the HLA complex influence T1D risk, albeit to a lesser degree than the class II genes. We have previously shown that allele 3 of microsatellite...

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PMID: 12595901
DOI: 10.1038/sj.gene.6363917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLA-DQB1, -DQA1 and -DRB1.PMID 12595901Read ↗

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A second component of HLA-linked susceptibility to type 1 diabetes maps to class I region.Semantic proximity Read ↗

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