Article
Association of restless legs syndrome variants in Korean patients with restless legs syndrome.
Sleep - 1 Dec 2013
Kim Myeong-Kyu, Cho Yong Won, Shin Won Chul, Cho Jae Wook, Shon Young Min, Kim Jee Hyun, Yang Kwang Ik, Earley Christopher J, Allen Richard P
Abstract excerpt
STUDY OBJECTIVES: Recent genome-wide association studies (GWAS) for Caucasians identified several allelic variants associated with increased risk of developing restless legs syndrome (RLS), also known as Willis-Ekbom disease. Although the pathogenic mechanisms of RLS are not entirely understood, it is becoming increasingly evident that many diseases such as RLS can be attributed to an epistasis. The study...
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