Article
Genetic variants in the angiopoietin-2 gene are associated with increased risk of ARDS.
Intensive care medicine - 1 Jun 2009
Su Li, Zhai Rihong, Sheu Chau-Chyun, Gallagher Diana C, Gong Michelle N, Tejera Paula, Thompson B Taylor, Christiani David C
Abstract excerpt
OBJECTIVE: Angiopoietin-2 (Ang-2) is a potent regulator of vascular permeability and inflammation in acute lung injury and acute respiratory distress syndrome (ARDS). Genetic variants in the Ang-2 gene may lead to altered activities of Ang-2 (or ANGPT2) gene. The aim of this study was to assess if genetic variants of Ang-2 are associated with the risk of ARDS. DESIGN: Unmatched, case-control study nested within a...
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