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Article

HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering.

Journal of virology - 1 May 2009

Matthews Philippa C, Leslie Alasdair J, Katzourakis Aris, Crawford Hayley, Payne Rebecca, Prendergast Andrew, Power Karen, Kelleher Anthony D, Klenerman Paul, Carlson Jonathan, Heckerman David, Ndung'u Thumbi, Walker Bruce D, Allen Todd M, Pybus Oliver G, Goulder Philip J R

Abstract excerpt

The selection of escape mutations has a major impact on immune control of infections with viruses such as human immunodeficiency virus (HIV). Viral evasion of CD8(+) T-cell responses leaves predictable combinations of escape mutations, termed HLA "footprints." The most clearly defined footprints...

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Identifiers

PMID: 19244334
DOI: 10.1128/JVI.02017-08
PMCID: PMC2668443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19244334-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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