Article

Associations of functional HLA class I groups with HIV viral load in a heterogeneous cohort

2022-06-23

Abstract excerpt

Human Leucocyte Antigen (HLA) class I alleles are the main host genetic factors involved in controlling HIV-1 viral load (VL). Nevertheless, HLA diversity has proven a significant challenge in association studies. We assessed how accounting for binding affinities of HLA class I alleles to HIV-1 peptides facilitate association testing of HLA with HIV-1 VL in a heterogeneous cohort from the Strategic Timing of AntiR...

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Literature Corpus work: b4d7438b-9a54-5075-8d1e-ad57292a3e59
DOI: 10.1101/2022.06.21.22276431

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