Article
Association analysis of glycine- and serine-related genes in a Japanese population of patients with schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 30 Apr 2009
Ohnuma Tohru, Shibata Nobuto, Maeshima Hitoshi, Baba Hajime, Hatano Tokiko, Hanzawa Ryo, Arai Heii
Abstract excerpt
Differences in the levels of the glutamate-related amino acids glycine and serine in brain/plasma between schizophrenic patients and normal subjects and changes in the plasma concentrations of these amino acids according to the clinical course have been reported. It has been hypothesized that glycine and serine metabolism may be altered in schizophrenia. In fact, some genes related to the metabolism of these...
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