Article
No genetic association between SLC7A10 and Japanese patients with schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Dec 2011
Takebayashi Yuto, Ohnuma Tohru, Hanzawa Ryo, Shibata Nobuto, Maeshima Hitoshi, Baba Hajime, Hatano Tokiko, Hotta Yuri, Kitazawa Maiko, Higa Motoyuki, Arai Heii
Abstract excerpt
Disrupted glutamatergic neurotransmission may be a pathophysiological feature in the brains from patients with schizophrenia, and glutamatergic amino acids including D-serine have been found to be involved in pathophysiology. Endogenous and exogenous D-serine have shown potential as biological markers for the pathophysiology of schizophrenia and especially as a therapeutic strategy in treatment-resistant...
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