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Article

Correlation of functional GRIN2A gene promoter polymorphisms with schizophrenia and serum D-serine levels.

Gene - 15 Aug 2015

Liu Rui, Dang Wei, Du Ying, Zhou Qiong, Liu Zhaohui, Jiao Kai

Abstract excerpt

Schizophrenia is a severe, complex mental disorder. Abnormal glutamate neurotransmission mediated by decreased expression of N-methyl-d-aspartic acid receptors (NMDArs) and its endogenous co-agonist d-serine (d-Ser) has been proposed as one of the hypotheses of the pathogenesis of schizophrenia. GRIN2A gene promoter polymorphism causes changes in the regulation of the expression of NMDAr subunit genes. Our study...

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Identifiers

PMID: 25958346
DOI: 10.1016/j.gene.2015.05.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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