Article
Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia.
BMC psychiatry - 18 Jul 2008
Deng Xiangdong, Sagata Noriaki, Takeuchi Naoko, Tanaka Masami, Ninomiya Hideaki, Iwata Nakao, Ozaki Norio, Shibata Hiroki, Fukumaki Yasuyuki
Abstract excerpt
BACKGROUND: Based on the glutamatergic dysfunction hypothesis for schizophrenia pathogenesis, we have been performing systematic association studies of schizophrenia with the genes involved in glutametergic transmission. We report here association studies of schizophrenia with SLC1A4, SLC1A5 encoding neutral amino acid transporters ASCT1, ASCT2, and SLC6A5, SLC6A9 encoding glycine transporters GLYT2, GLYT1,...
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