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Article

Analysis of correlation between serum D-serine levels and functional promoter polymorphisms of GRIN2A and GRIN2B genes.

Neuroscience letters - 13 Feb 2006

Iwayama Yoshimi, Hashimoto Kenji, Nakajima Mizuho, Toyota Tomoko, Yamada Kazuo, Shimizu Eiji, Itokawa Masanari, Hoshika Akinori, Iyo Masaomi, Yoshikawa Takeo

Abstract excerpt

D-Serine is an endogenous coagonist that increases the opening of N-methyl-D-aspartate (NMDA)-type glutamate receptor channels. We previously reported a reduction of D-serine serum levels in schizophrenia, supporting the disease hypothesis of NMDA receptor-mediated hypo-neurotransmission. The serum levels of D-serine are thought to reflect brain d-serine content. It is important to understand whether there is a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16266783
DOI: 10.1016/j.neulet.2005.10.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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