Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast.

PloS one - 21 May 2008

Natsume Toyoaki, Tsutsui Yasuhiro, Sutani Takashi, Dunleavy Elaine M, Pidoux Alison L, Iwasaki Hiroshi, Shirahige Katsuhiko, Allshire Robin C, Yamao Fumiaki

Abstract excerpt

Specialized chromatin exists at centromeres and must be precisely transmitted during DNA replication. The mechanisms involved in the propagation of these structures remain elusive. Fission yeast centromeres are composed of two chromatin domains: the central CENP-A(Cnp1) kinetochore domain and fla...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Centromere
Share to Chromatin Immunoprecipitation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Fungal

Share to DNA Polymerase I

Share to Histone Deacetylases

Share to Myeloid Cell Leukemia Sequence 1 Protein

Share to Proto-Oncogene Proteins c-bcl-2

Source

Open in PubMed Open full text

Identifiers

PMID: 18493607
DOI: 10.1371/journal.pone.0002221
PMCID: PMC2376062

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18493607-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast.PMID 18493607Read ↗

Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation.Semantic proximity Read ↗

A NASP (N1/N2)-related protein, Sim3, binds CENP-A and is required for its deposition at fission yeast centromeres.Semantic proximity Read ↗

The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres.Semantic proximity Read ↗

The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast.Semantic proximity Read ↗

Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.Semantic proximity Read ↗

Genome-wide analysis reveals a cell cycle-dependent mechanism controlling centromere propagation.Semantic proximity Read ↗

Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast.Semantic proximity Read ↗

The Schizosaccharomyces pombe HIRA-like protein Hip1 is required for the periodic expression of histone genes and contributes to the function of complex centromeres.Semantic proximity Read ↗

A new role for the transcriptional corepressor SIN3; regulation of centromeres.Semantic proximity Read ↗

Fission yeast Scm3: A CENP-A receptor required for integrity of subkinetochore chromatin.Semantic proximity Read ↗

A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast.Semantic proximity Read ↗

Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.