Article
CENP-C functions as a scaffold for effectors with essential kinetochore functions in mitosis and meiosis.
Developmental cell - 1 Sept 2009
Tanaka Koichi, Chang Hui Li, Kagami Ayano, Watanabe Yoshinori
Abstract excerpt
The conserved kinetochore protein CENP-C plays a fundamental role in chromosome segregation, but its specific functions remain elusive. We have gained insights into the role of CENP-C through identification of interacting effector proteins required for kinetochore function in fission yeast. Fta1/CENP-L is a primary effector that associates directly with Cnp3/CENP-C, and ectopic localization of Fta1 largely...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
