Article
Simultaneous analysis of multidrug resistance 1(MDR1) C3435T, G2677T/A, and C1236T genotypes in Hamadan City population, West of Iran.
Iranian biomedical journal - 1 Jan 2015
Saidijam Massoud, Mahjub Hossein, Shabab Nooshin, Yadegarazari Reza
Abstract excerpt
BACKGROUND: One of the limitations in the treatment of common diseases such as cancer chemotherapy is development of multidrug resistance (MDR). Polymorphisms could alter the expression level of MDR1 gene, which plays an important role in MDR. In this research, the frequency of C3435T, C1236T, and G2677T/A polymorphisms of MDR1 gene was investigated in a large group of population from Hamadan city to provide a...
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