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Article

Association of a polymorphism in the ABCB1 gene with Parkinson's disease.

Parkinsonism & related disorders - 1 Jul 2009

Westerlund Marie, Belin Andrea Carmine, Anvret Anna, Håkansson Anna, Nissbrandt Hans, Lind Charlotta, Sydow Olof, Olson Lars, Galter Dagmar

Abstract excerpt

The ATP-binding cassette, sub-family B, member 1 (ABCB1) gene encoding the protein P-glycoprotein (P-gp) has been implicated in the pathophysiology of Parkinson's disease (PD) due to its role in regulating transport of endogenous molecules and exogenous toxins. In the present study, we analyzed the ABCB1 single nucleotide polymorphisms (SNPs) 1236C/T (exon 12), 2677G/T/A (exon 21) and 3435C/T (exon 26) in 288...

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Source

Identifiers

PMID: 19196542
DOI: 10.1016/j.parkreldis.2008.11.010

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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