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Article

Ethnicity-related polymorphisms and haplotypes in the human ABCB1 gene.

Pharmacogenomics - 1 Jan 2007

Kimchi-Sarfaty Chava, Marple Andrew H, Shinar Shiri, Kimchi Avraham M, Scavo David, Roma M Isabella, Kim In-Wha, Jones Adam, Arora Mili, Gribar John, Gurwitz David, Gottesman Michael M

Abstract excerpt

INTRODUCTION: The human multidrug resistance gene ATP-binding cassette B1 (ABCB1) codes for P-glycoprotein (P-gp), an important membrane-bound efflux transporter known to confer anticancer drug resistance as well as affect the pharmacokinetics of many drugs and xenobiotics. A number of single nucleotide polymorphisms (SNPs) have been identified throughout the ABCB1 gene that may have an effect on P-gp expression...

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, MDR

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Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 17187507
DOI: 10.2217/14622416.8.1.29
PMCID: PMC1876748

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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