Article
Genetic analysis of coding SNPs in blood-brain barrier transporter MDR1 in European Parkinson's disease patients.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Apr 2009
Funke Claudia, Soehn Anne S, Tomiuk Juergen, Riess Olaf, Berg Daniela
Abstract excerpt
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons and the presence of intracytoplasmic inclusions (Lewy bodies). Iron, which is elevated in the substantia nigra of PD patients, seems to be of pivotal importance, because of its capacity to enhance the amplification of r...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
