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Article

ABCB1 gene variants as risk factors and modulators of age of onset of demyelinating disease in Mexican patients.

Neurologia - 1 Mar 2023

Guerrero Camacho J L, Corona Vázquez T, Flores Rivera J J, Ochoa Morales A, Martínez Ruano L, Torres Ramírez de Arellano I, Dávila Ortiz de Montellano D J, Jara Prado A

Abstract excerpt

INTRODUCTION: The C1236T, G2677T/A, and C3435T variants of the ABCB1 gene alter the functioning of P-glycoprotein and the transport of endogenous and exogenous substances across the blood-brain barrier, and act as risk factors for some neurodegenerative diseases. This study aimed to determine the association between demyelinating disease and the C1236T, G2677T/A, and C3435T variants of ABCB1 and its haplotypes...

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Identifiers

PMID: 35256320
DOI: 10.1016/j.nrleng.2020.05.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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