Article
Analysis of MDR1 haplotypes in Parkinson's disease in a white population.
Neuroscience letters - 6 Dec 2004
Tan Eng-King, Drozdzik Marek, Bialecka Monika, Honczarenko Krystyna, Klodowska-Duda Gabriela, Teo Y Y, Tang Kun, Wong Li-Peng, Chong Samuel S, Tan Chris, Yew Kenneth, Zhao Yi, Lee Caroline Gl
Abstract excerpt
The MDR1 multidrug transporter is important in regulating environmental xenobiotics and hence may play a causative role in Parkinson's disease (PD). MDR1 haplotype comprising 2677 G > T/A and 3435 C > T may be protective against PD. Using a case control methodology, we investigated the association of MDR1 haplotypes (single nucleotide polymorphisms (SNPs) 2677 G > T/A and 3435 C > T) in a Polish PD population....
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