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Article

MDR1 variants and risk of Parkinson disease. Association with pesticide exposure?

Journal of neurology - 1 Jan 2009

Zschiedrich Katja, König Inke R, Brüggemann Norbert, Kock Norman, Kasten Meike, Leenders Klaus L, Kostić Vladimir, Vieregge Peter, Ziegler Andreas, Klein Christine, Lohmann Katja

Abstract excerpt

The multidrug resistance protein 1 (MDR1 or ABCB1) gene encodes a P-glycoprotein that protects the brain against neurotoxicants. Certain MDR1 genetic variants are known to compromise the function of this transporter and may thus be associated with Parkinson disease (PD). We therefore conducted a large case-control study investigating the potential relationship between MDR1 variants and PD. We determined the...

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Source

Identifiers

PMID: 19184162
DOI: 10.1007/s00415-009-0089-x

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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