Article
Genetic polymorphisms of heme-oxygenase 1 (HO-1) may impact on acute kidney injury, bronchopulmonary dysplasia, and mortality in premature infants.
Pediatric research - 1 Jun 2015
Askenazi David J, Halloran Brian, Patil Neha, Keeling Susan, Saeidi Behtash, Koralkar Rajesh, Ambalavanan Namasivayam
Abstract excerpt
BACKGROUND: Heme oxygenase 1 (HO1) catalyzes heme degradation, and offers protection for several organs, including the kidney. Genetic polymorphisms of HO-1 are associated with poor clinical outcomes in several populations. METHODS: POPULATION: We prospectively enrolled 117 premature infants (bir...
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