Article
Replication of genome-wide association study identified seven susceptibility genes, affirming the effect of rs2856717 on renal function and poor outcome of IgA nephropathy.
Nephrology (Carlton, Vic.) - 1 Oct 2017
Wang Wei, Li Guisen, Hong Daqing, Zou Yurong, Fei Deng, Wang Li
Abstract excerpt
AIM: Meta-analysis of data from a genome-wide association study (GWAS) identified seven single nucleotide polymorphisms (SNPs) as strong predictors of IgA nephropathy (IgAN). To replicate the association of these seven SNPs and understand whether they influence the clinical characteristics of IgAN, a case-control study including 521 IgAN patients and 535 controls was conducted in a Western Han cohort. METHODS:...
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