Article
A TLR2 polymorphism is associated with type 1 diabetes and allergic asthma.
Genes and immunity - 1 Mar 2009
Bjørnvold M, Munthe-Kaas M C, Egeland T, Joner G, Dahl-Jørgensen K, Njølstad P R, Akselsen H E, Gervin K, Carlsen K C L, Carlsen K H, Undlien D E
Abstract excerpt
Type 1 diabetes (T1D) and allergic asthma are immune-mediated diseases. Pattern recognition receptors are proteins expressed by cells in the immune system to identify microbial pathogens and endogenous ligands. Toll-like receptors (TLRs) and CD14 are members of this family and could represent a molecular link between microbial infections and immune-mediated diseases. Diverging hypotheses regarding whether there...
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