Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequencies of genetic polymorphisms of TLR4 and CD14 and of HLA-DQ genotypes in children with celiac disease, type 1 diabetes mellitus, or both.

Journal of pediatric gastroenterology and nutrition - 1 Sept 2008

Dezsofi A, Szebeni B, Hermann C S, Kapitány A, Veres G, Sipka S, Körner A, Madácsy L, Korponay-Szabó I, Rajczy K, Arató A

Abstract excerpt

OBJECTIVES: Besides the central role of the adaptive immune system, a disturbance of innate immunity is also involved in the pathogenesis of celiac disease (CD). Inasmuch as CD and type 1 diabetes mellitus (T1DM) frequently coexist because of a common genetic predisposition, our aim was to study the frequency of CD14 C-260T and TLR4 A+896G single nucleotide polymorphisms (SNPs) and the distribution of HLA-DQ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Celiac Disease
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comorbidity

Share to Diabetes Mellitus, Type 1

Share to HLA-DQ Antigens

Share to Lipopolysaccharide Receptors

Share to Polymorphism, Restriction Fragment Length

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 18728522
DOI: 10.1097/MPG.0b013e31816de885

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequencies of genetic polymorphisms of TLR4 and CD14 and of HLA-DQ genotypes in children with celiac disease, type 1 diabetes mellitus, or both.PMID 18728522Read ↗

Toll-like Receptors and Celiac Disease.Semantic proximity Read ↗

The Usefulness of Genotyping of Celiac Disease-Specific HLA among Children with Type 1 Diabetes in Various Clinical Situations.Semantic proximity Read ↗

A TLR2 polymorphism is associated with type 1 diabetes and allergic asthma.Semantic proximity Read ↗

Risk of celiac disease in children with type 1 diabetes is modified by positivity for HLA-DQB1*02-DQA1*05 and TNF -308A.Semantic proximity Read ↗

Contribution of KIR genes, HLA class I ligands, and KIR/HLA class I ligand combinations on the genetic predisposition to celiac disease and coexisting celiac disease and type 1 diabetes mellitus.Semantic proximity Read ↗

Association analysis between the TLR9 gene polymorphism rs352140 and type 1 diabetes.Semantic proximity Read ↗

The association between the HLA-G 14-bp insertion/deletion polymorphism and type 1 diabetes.Semantic proximity Read ↗

Association of toll-like receptor 4 polymorphisms with type 2 diabetes mellitus.Semantic proximity Read ↗

HLA Genotyping in Children With Celiac Disease Allows to Establish the Risk of Developing Type 1 Diabetes.Semantic proximity Read ↗

An influence of HLA-A, B, DR, DQ, and MICA on the occurrence of Celiac disease in patients with type 1 diabetes.Semantic proximity Read ↗

Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors.Semantic proximity Read ↗

Association between HLA alleles and risk of celiac disease in Iranian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.