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Article

Toll-like receptor heterodimer variants protect from childhood asthma.

The Journal of allergy and clinical immunology - 1 Jul 2008

Kormann Michael S D, Depner Martin, Hartl Dominik, Klopp Norman, Illig Thomas, Adamski Jerzy, Vogelberg Christian, Weiland Stephan K, von Mutius Erika, Kabesch Michael

Abstract excerpt

BACKGROUND: Early exposure to microbes reduces the risk for asthma. Toll-like receptors (TLRs) represent a major group of receptors for the specific recognition of pathogen-associated molecular patterns of microbes capable of activating innate and adaptive immunity. OBJECTIVE: Because TLRs can influence key events in the induction and perpetuation of asthma and atopy, we sought to determine whether genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18547625
DOI: 10.1016/j.jaci.2008.04.039

Genes

TLR1
TLR6
TLR10
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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