Article
Association of the polymorphism for Toll-like receptor 2 with type 1 diabetes susceptibility.
Annals of the New York Academy of Sciences - 1 Dec 2004
Park Yongsoo, Park Sukyung, Yoo Eunkyung, Kim Dukhee, Shin Hyongdoo
Abstract excerpt
Type 1 diabetes mellitus (T1DM) is a T cell-mediated autoimmune disease in which pancreatic beta cells are selectively destroyed. Although autoimmune diseases are driven by inappropriate adaptive immunity, innate immunity may play a role in the development of T1DM. We investigated the association of the genes for toll-like receptor 2 (TLR2), one of the key surface receptors on innate effectors, with T1DM in...
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