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Article

Association of toll-like receptor 4 polymorphisms with type 2 diabetes mellitus.

Inflammation - 1 Feb 2013

Jiang Zhao-Shun, Wang Su-Xia, Jia Hong-Xia, Wang Jing, Liu Yuan-Tao

Abstract excerpt

Type 2 diabetes mellitus (T2DM) is characterized by a chronic low-grade inflammatory state. Toll-like receptor 4 (TLR4) is a critical mediator of innate immunity. Polymorphisms in TLR4 gene have been shown to be associated with impaired inflammatory response. Here, we investigated the association of TLR4 polymorphisms with T2DM. Four TLR4 polymorphisms (+986A/G, +1196C/T, +3725G/C, and +11367G/C) were genotyped...

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Source

Identifiers

PMID: 22956123
DOI: 10.1007/s10753-012-9541-7

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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